Sexuality and Depression Learn about how depression can affect your sexuality and what you can do about it. Never adjust your dosage without speaking with your doctor first. Since this study did not indicate whether or not the results were statistically significant, more studies may necessary to determine whether vilazodone is less likely to cause sexual side effects compared Paxil and sexual dysfunction SSRIs. Out of 81 citations, 4 studies were included. Migraines and Vertigo Migraines: Paroxetine should be the last SSRI of choice as it has the greatest incidence of causing sexual dysfunction.