Corticosteroids in pulmonary tuberculosis. Idiopathic Pulmonary Fibrosis; IV: The clinical and radiographic manifestations of pulmonary tuberculosis are often slow to resolve despite fully effective antimicrobial chemotherapy. In the s, the recognition that lung damage in tuberculosis TB is mainly due to a prolonged host inflammatory response led to a series of controlled clinical trials of adjunctive corticosteroids administered during the early phase of TB chemotherapy. Receive exclusive offers Lung penetration of methylprednisolone updates from Oxford Academic. Home Publications Conferences Register Contact.